Cycling off every few months prevents receptor fatigue and helps maintain your natural hormone rhythms
GLP-1 receptor agonists work by mimicking the action of naturally occurring incretin hormones, which influence glucose metabolism, gastric emptying, and appetite regulation
They operate at fundamentally different points in the endocrine cascade, and conflating them leads to failed research protocols
And frankly, if you try to respond that you dont need any rest days, Im just going to be blunt
2 Adverse side effects of Tirzepatide are diverse, including acute pancreatitis, cholelithiasis, severe hypoglycemia, and cholecystitis which have been reported to be present in less than 1% of all doses of Tirzepatide, along with anaphylaxis in some patients