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The evidence currently available indicates that GLP-1 RA could add to the arsenal available to address persistent gaps in the care of people living with T2DM with, or at the risk of, developing CKD and to reduce the residual renal risk present in those who have already developed CKD
Are there side effects for GLP-1s?] [Cut to Tony] Tony, speaking: GLP-1s are incredibly prevalent and growing increasingly more so because they are so effective [On-screen text: GLP-1 medications are most effective with diet and exercise modifications] [Cut to people cooking together and riding bicycles.] Tony, speaking: especially when combined with diet and exercise modifications
Johansen NJ, Dejgaard TF, Lund A et al (2020) Efficacy and safety of meal-time administration of short-acting exenatide for glycaemic control in type 1 diabetes (MAG1C): a randomised, double-blind, placebo-controlled trial
Key genes promoting ROS/RNS production: Thbs1 , S100a8 and Nos2 , were significantly downregulated, while the glutathione S-transferase gene Gsta2 , involved in cellular anti-oxidative defence, was upregulated 36,37
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