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Previous scRNA-seq studies of LPC and CPZ models have described distinct disease-associated oligodendrocyte (DAO) states, including similar transcriptional changes to those in Alzheimers disease models, but have not directly compared LPC and CPZ 8,9,10
Um, do you have any other thoughts on this that we didnt get to in this episode
doi: 10.1016/j.abb.2021.108926 169 YanSHuiYLiJXuXLiQWeiH
1:2500, Abcam, Cambridge, UK), Drp-1 (1:2000, Novus Biotechnology, Littleton, CO, USA), Opa-1 (1:2000, Novus Biotechnology, Littleton, CO, USA), LC3A/B (1:2000, Cell Signaling Technology, Danvers, MA, USA), Tom-20 (1:2000, Santa Cruz Biotechnology, Dallas, TX, USA) and MnSOD (1:2000, Millipore, Billerica, MA, USA), Pink-1 (1:1000, BioVision Incorporated, Milpitas, CA, USA), Fis-1 (1:500, Santa Cruz Biotechnology, Dallas, TX, USA) and Parkin (1:500, Cell Signaling Technology, Danvers, MA, USA) for overnight
