Phase 2 data published in the New England Journal of Medicine (2023) demonstrated substantial weight loss in adults with obesity, but the medicine is not yet approved for clinical use in the UK
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Of note, most of the pharmacological testing of these GLP1-based compounds has been implemented so far in male models of obesity 33,34,35,48 , with limited insight into their effects in female-specific metabolic conditions
6 luglio 2023 [citato 28 luglio 2024];14:1149328
Endocrine and metabolic effects of GLP-1 receptor agonists on women with PCOS, a narrative review