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Sleep architecture: GHRH administration enhances slow-wave sleep duration in both young and elderly subjects (Steiger et al., 1992), supporting the PM dosing strategy
The most commonly reported side effects in clinical trials are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which are typically most pronounced during the dose titration phase and tend to improve over time
Weight loss exceeding two pounds weekly after the first month might seem like good news, but it increases risks
Regarding the specific dosing regimens, exenatide was administered with a single 20 g loading dose followed by fixed twice-daily injections of 10 g for 12 weeks
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