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Lim, R., Beekley, A., Johnson, D

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In Stxbp1 K98Q knock-in mice, the upregulation of STXBP1 K98cr reduces the binding with syntaxin-1B(STX1B), leading to a decreased assembly of soluble NSF attachment protein receptors (SNAREs) in presynaptic active zone and subsequent inhibition vesicle release, thereby promoting epilepsy formation

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