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However, it remains unclear whether these natriuretic responses are direct effects of GLP-1RA because a lack of GLP-1R in the proximal tubules has been reported (Ronn et al., 2017)

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Association of bile duct and gallbladder diseases with the use of Incretin-based drugs in patients with type 2 diabetes mellitus

In October, Eli Lillys Zepbound and Mounjaro were removed from the drug shortage list after nearly two years, though the FDA warned that there still may be intermittent localized supply disruptions. The removal from the listwhich bars outsourcing facilities from producing compounded versionsspurred the Outsourcing Facilities Association to file a lawsuit against the FDA, saying the move will deprive much of the public of access to a needed medicine. In response, the FDA agreed to reevaluate the situation and will allow compounding to continue during this period