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[7] Population pharmacokinetic modeling reveals a biphasic disposition (distribution half-life 15-30 minutes
The choice of treatment should be individualised, considering the underlying cause, symptom severity, patient preference, and practical factors such as access to healthcare facilities for regular injections
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This timeline allows the body to adapt to improved NAD+ availability and mitochondrial function
Importantly, food intake remained unchanged in treated animals, suggesting the compound's effects relate to energy expenditure pathways rather than appetite
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