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Decitabine, an analog of 5-azacytidine, is also a potent DNMT1 inhibitor with a more favorable safety profile but decitabine is rapidly deaminated and inactivated by cytosine deaminase, if taken orally

Michigan, Rhode Island, and Wisconsin are planning or considering restrictions, according to KFFs most recent survey

Insurance Coverage Insurance coverage for weight loss medications varies significantly by plan

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Most common are GI: nausea, decreased appetite, constipation, occasional diarrhea, and reflux typically mild to moderate and concentrated during dose escalation