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Under thermal stress, an increase in oxidative stress was observed in the myocytes of Micropterus salmoides , however, intervention of astaxanthin exerted a notable alleviating effect on oxidative stress

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It is hoped that ongoing trials like SUMMIT, which is investigating tirzepatide in participants with HFpEF and obesity, will provide more evidence on incretin-based medications in HFpEF

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Rather than relying solely on calorie restriction and exercise plans, healthcare providers now have access to medications that target some of the biological mechanisms involved in hunger, appetite regulation, blood sugar control, and weight gain