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The impact will also be felt more broadly within the healthcare sector
We confirm that co-treatment with 5FU and mitochondrial inhibitors, particularly CI inhibitors IACS-010759 (a specific CI inhibitor under clinical evaluation 51 ) and metformin hydrochloride (a treatment for diabetes that inhibits CI 52 ), increases growth arrest and death in CRC cells (Fig
Because the two act on separate receptors, combining them is intended to stimulate the GH axis from two angles at once
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