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Whole grains can also provide essential vitamins and minerals, such as the B vitamins thiamine, riboflavin, and niacinall of which play a key role in metabolism

Potential impact and next steps By delivering greater weight reduction and metabolic benefits while maintaining a favorable safety profile, the authors say this higher dose could help more people reach their health goals and reduce the burden of obesity-related complications worldwide

In humans, pantothenic acid deficiency has been induced experimentally by co-administering a pantothenic acid antagonist and a pantothenic acid-deficient diet

doi: 10.1016/j.arr.2023.101979 24 RubinR

Dropping back to the previous dose is also reasonable