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Furthermore, the role of DMH GLP-1R neurons or LepR neurons in sensory-specific satiety, a phenomenon in which repeated exposure to a particular taste reduces food intake, is an area for further study
Commenting on the results, Novo Nordisk chief scientific officer Martin Holst Lange pointed out that the weight loss numbers were comparable to what's achievable through injection -- no needles required
In comparative studies, this combination has demonstrated additive effects on weight loss by targeting two distinct neuroendocrine pathways: the hindbrain (area postrema) via amylin agonism and the hypothalamus via GLP-1 agonism
