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These are promising interventions, but we do not have lots of studies in humans with big numbers and exact methods of amounts/ method of giving/ frequency

Nile grass rats ( Arvicanthis niloticus ), a diurnal rodent, exposed to short photoperiod (5 h light/19 h dark) for 6 weeks presented reduced saccharin preference, higher immobility time in the forced swim test, and no changes on time spent in the light side of the dark/light box in comparison to controls (Figure 1), rats develop into depressive-like phenotypes (i.e., anhedonia, sexual dysfunction, increased immobility in the forced swim test) ( Landgraf et al

Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability

Structure of the human FOXO4-DBD-DNA complex at 1.9 resolution reveals new details of FOXO binding to the DNA

In the proposed study, it forms an imine bond with free amino groups of gelatin resulting in the formation of the nanohydrogel (Sarika and James, 2015)