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Weight Loss: Semaglutide promotes a feeling of fullness, reducing food intake and promotes significant weight loss, making it an ideal option for patients with type 2 diabetes who also struggle with weight management

Therefore, combining SGLT2 inhibitors with drugs acting via different mechanisms might be the most effective approach for major weight loss and address counter-regulatory mechanisms that maintain body weight [41]

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Most people ingest more sodium chloride than recommended, which can result in water retention, blood volume expansion, edema (the accumulation of excess fluid in the body), and elevated blood pressure