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Participants receiving cagrilintide were roughly 28 times more likely to experience some form of injection site reaction compared to those receiving placebo injections

Conversely, Tang et al

10.1186/s12989-019-0307-3 Part Fibre Toxicol

The full-length three-dimensional structure of LONP1 was first resolved in 2016 by the Kereche team using cryo-electron microscopy, revealing its unique hexameric architecture: the P-domains form a bowl-shaped cavity, topped by the AAA+ modules, while the N-terminal domains create a narrow channel [21] (Fig