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Severa, M., Zhang, J., Giacomini, E., Rizzo, F., Etna, M

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Figures shown are based on internal clinical data and do not constitute a promise or guarantee of specific results

The activity of DHODH influences the vulnerability of cancer cells with low GPX4 levels to ferroptosis, likely due to DHODH-mediated utilization of COQ10 as an electron acceptor in HT1080 and NCI-H226 (human lung cancer cell line) cells [13]