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Over time, patients may lose fat while maintaining muscle mass, creating a leaner physique even when the scale changes slowly
Prez de la Lastra et al., 2021)
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In one study, it was demonstrated that exendin-4 prevented LPS-induced depressive-like symptoms in rats and displayed antidepressant-like properties measured in the forced swim test, but this effect was not mediated by the modulation of neuroinflammatory processes, since the levels of IL-1 and TNF- were not affected by exendin-4 treatment [67]
In an interview with The Canadian Press in late December, Novo Nordisk Canada president Vince Lamanna declined to give any details about the patent lapse, citing intellectual property confidentiality
