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Holmium laser enucleation of the prostate Holmium laser enucleation of the prostate (HoLEP) is a urological surgery that uses a laser to remove the excess prostate tissue and relieve pressure on the urethra

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In the initial consistency meta-analysis, three of these variants reached genome-wide significance (rs7976914, rs4237904, and rs4970833) [143, 144]