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A Phase IIb study comparing cotadutide with the GLP-1R mono-agonist liraglutide showed that, after 54 weeks, cotadutide produced similar HbA 1c reductions (cotadutide vs liraglutide: 13.0 mmol/mol vs 12.8 mmol/mol [1.19% vs 1.17%]) but greater bodyweight reductions than liraglutide (5.02% vs 3.33%) [6]
39-43 Since inflammation appears to play a role in cardiometabolic, immunologic, and neurodegenerative diseases, targeting it as a mechanism of disease could aid in managing multiple disorders with just a single drug
Serum adipokines in inflammatory bowel disease
we would need these studies before we could say whether semaglutide is the cause of the reported sex drive changes
A randomized controlled pilot trial of oral N-acetylcysteine in children with autism. Biological psychiatry 71, no
