This finding aligns with previous studies, such as the SUSTAIN-6 trial [32], which showed a neutral effect of semaglutide on overall arrhythmia risk but suggested a trend toward reduced AF incidence
To corroborate these findings prior to targeting the murine VSMC Glp1r , we analyzed human and murine renal transcriptomic datasets (17, 18)
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Similar to results from DAT;NuTRAP mice, KEGG analysis returned terms associated with the upregulation of pathways involved in inflammation response (Fig