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2023;13(3):e061807

OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN2

Additionally, decreased glycolysis has been observed in CD8+ T cells at rest and after activation (254), CD4+ T cells at rest (254), blood and urine samples (187), and PBMCs (388)

Injecting too early

avoid injecting through clothing Use a swift, confident injection technique rather than hesitant, slow insertion Avoid injecting into areas with scarring, bruising, or active skin lesions Always use a new needle for each injection and follow local guidance for safe sharps disposal Post-injection care: Apply a cool compress (not ice directly on skin) to reduce swelling or discomfort Avoid rubbing or massaging the injection site immediately afterwards Wear loose-fitting clothing to minimise irritation For generalised burning or itching: Emollients and moisturisers : Regular application of fragrance-free, hypoallergenic moisturisers can soothe dry or irritated skin Antihistamines : Over-the-counter oral antihistamines (e.g., cetirizine, loratadine) may provide relief if itching is prominent