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Semaglutide, a GLP-1 receptor agonist, is studied extensively in metabolic and weight-related research

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The SUSTAIN-6 trial published in 2016 showed that participants receiving weekly Ozempic (semaglutide) lost an average of 3-5 kg (8-11 lbs) after a two-year period (3)

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Accessed at www.healthline.com/health-news/glp-1-drugs-benefits-risks-health-outcomes

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Figure 1 Figure 2 3 Mechanisms of action for GLP-1R agonists to control food intake GLP-1R agonists primarily act to reduce body weight by suppressing energy intake

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