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In the Phase 3 REDEFINE 1 trial, cagrilintide monotherapy achieved 11.8% average weight loss over 68 weekscomparable to semaglutide but with a notably lower incidence of nausea and vomiting, making it a potential option for patients who dont tolerate GLP-1 medications well
This prespecified analysis explored the effect of semaglutide on the primary composite endpoint of MACE for patients at risk for substantial fibrosis as indicated by an FIB-4 score of 1.3 or greater
Circulating plasma levels rose 1.6-fold
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If this happens once per year, that is the cost of a nice dinner out
How do GLP-1s work for weight loss
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