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It is the same cascade native IGF-1 and insulin partially share, which is why IGF-1 LR3 is frequently used as a research tool for studying mTOR-dependent cellular processes under sustained receptor activation
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Wendell PL (1970)
These structures were then subjected to energy minimization using the Gaussian16 55 software package, which optimized the geometries to ensure that the pAcF had the most stable conformations before integration into Rosetta
D.ShaioM
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