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Recent decades have seen a dramatic increase in the share of the world population suffering from overweight and obesity (Wong et al., 2022)

Maintaining adequate hydration before and after administration may support normal metabolic and detoxification processes during therapy

Saikosaponin A and D inhibit adipogenesis via the AMPK and MAPK signaling pathways in 3T3-L1 adipocytes

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Oxidative stress is manifested through NOX2/ROS signaling, leading to excessive ROS production, lipid peroxidation, SOD inhibition, and a redox imbalance between glutathione and oxidized glutathione (Skibska et al., 2022)