Sugiyama T, Sadzuka Y, Nagasawa K, Ohnishi N, Yokoyama T, Sonobe T
By splitting an aptamer that binds to ATP and labeling each fragment with differently colored fluorophores, they were able to develop an assay that reports binding only when the two fluorophores are in proximity to each other, and thus eliminates background from non-specific binding events
Specifically, it was shown to potently stimulate insulin release in response to glucose, and to restrict glycemic excursion, beyond that of the GLP-1 albumin fusion composed of WT albumin, likely due to a higher concentration in plasma
the rate at which food moves through your gut)
She draws a parallel to bariatric surgery: "It's the same with bariatric surgery