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Combining two agents that each need their own titration stacks those dose-related effects, and no monitored study has characterised where the resulting ceiling sits
Dosage schedules at different frequencies are against safety recommendations
Patients self-injecting vitamin B12 without telling their GP, finds study A large proportion of patients with a vitamin B12 deficiency self-inject medication sourced online, citing difficulty with accessing treatment from GPs
These can lead to side effects or reactions that you may then associate with the B12 itself, even though B12 has nothing to do with them
One study compared the livers of healthy men to those with liver cirrhosis, and found the key difference was reduced glutathione levels (10)
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