Understanding what we know, and what we don't know, about long-term use helps you make informed decisions
Id say about 70% of the people I talk to who are using tesamorelin are doing it for body composition not because theyre HIV-positive
That number landed below the 25% target that Novo Nordisk had projected, causing brief concern among investors, but it still represents one of the largest weight loss outcomes ever achieved with a pharmacological intervention
As this is the first study to assess such measures, the predictive value of these markers will become even more solidified as future studies are completed and similar protein concentrations can be compared on new and even larger populations from the DRC, as well as konzo affected communities in other countries of sub-Saharan Africa
These observations, together with the fact that spine head size and geometry are associated with AMPA receptor content and maturation status (Matsuzaki et al., 2001), suggest that MET signaling may control many aspects of glutamatergic synapse development, including the timing of excitatory synapse maturation (Qiu et al., 2014)