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Based on available clinical data, retatrutide produced significantly greater weight loss (-24.2% at 48 weeks) than semaglutide (-16.0% at 68 weeks) in their respective trials
Phase 3 studies examining semaglutide specifically for NASH are ongoing
Dosing and Administration Currently orally administered semaglutide is approved by the US Food and Drug Administration (FDA), European Medicines Agency, Health Canada, Australia and Japan as an adjunct to diet and exercise to improve glycaemic control in adults with T2DM
Diabetes (2013) 62:27526
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