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Although numerous anti-depressive treatments are available, 30% of patients diagnosed with depression do not experience positive therapeutic effects with these therapies ( The gut is a key member of the gut-brain axis owing to its own enteric nervous system and its independent responses to the exterior environment and stress (Rao and Gershon, 2016)

10.1038/jhg.2016.20 19

If the manuscript is accepted, we will approve it for publication in Cardiovascular Diabetology

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For a maximum of 60 s, the rats were permitted to roam at 30, 50, and 70 cm from the end of the beam that contained the training bulb