During exosome formation, MSU crystal-stimulated neutrophils promote the synthesis of LTB4: cytosolic phospholipase A2 alpha translocates to the nuclear membrane, where it releases AA from membrane-bound phospholipids, whereas 5-lipoxygenase (5-LOX) is mobilized to the nuclear membrane, where it binds to 5-LOX-activating protein (FLAP) and acts on AA to produce leukotriene A4 (LTA4)
mansoni TGR (15 pmol/l) was revealed by determining the residual GR (A) and TrxR (C) activities of enzyme in the presence of 100 M NADPH and inhibitor at 0, 2, 4, 10, and 30 min incubation periods
This step can be confusing because it involves measurements, concentration, and unit conversions
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However, most patients were found in the late stage with metastasis, which made the prognosis worse