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Approval for Diabetes and Weight Management Over the past decade, three GLP-1/GIP receptor agonists liraglutide, semaglutide, and tirzepatide initially approved by the FDA for adults with type 2 diabetes, have also gained FDA approval for chronic weight management in people without diabetes, provided they meet specific criteria: a BMI of 30, or 27 with at least one weight-related condition such as hypertension, dyslipidemia, or type 2 diabetes

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Experimental data suggest a possible reduction in apoptotic signaling proteins and an increase in survival-related markers, hinting at a protective or growth-supportive role in cultured cells

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10.1111/j.1530-0277.2010.01237.x Alcohol Clin Exp Res