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Further optimization was carried out by using an aeris wide pore XB-C8 (100 4.6mm), 3.6 m column thermostated at 40C with a mobile phase containing gradient program with Pump A: (acetonitrile: methanol (50:50) % v/v) and Pump B: (0.2% formic acid in milli Q water (v/v))

California Proposition 65: No Proposition 65 warning was identified in the materials reviewed for this article

Animal studies show that mice prone to obesity have high NNMT levels in their white fat tissue

As a consequence, a number of significant mechanisms and dynamic forces that determine regulatory pathways have been overlooked

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