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But attributing that risk to semaglutide would be inaccurate

Humans: The most significant risk of GLP-1 usage is a very rare form of thyroid cancer, Medullary Thyroid Carcinoma (MTC)

Studies suggest that roughly 10% of patients discontinue treatment because of digestive symptoms.[5] Doctors often recommend small changes to help manage these side effects, such as eating smaller meals, eating slowly, stopping when you feel full, and avoiding high-fat foods

Glucose Control : Both GLP-1 agonists and metformin help to improve insulin sensitivity and reduce blood glucose levels