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Derived from a protein sequence associated with gastric peptides, BPC-157 is commonly explored in laboratory studies focused on connective tissue models, recovery processes, and biological signaling

The progressive drying and keratinization of the conjunctiva, particularly on the nasal and temporal conjunctiva, results in the development of irregularly shaped spots termed Bitot (bee toe) spots after the French physician, Pierre Bitot, who first described them

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This leads to the release and cytoplasmic translocation of p53, which can subsequently activate transcription-independent pro-apoptotic signaling (Figures 6A,B)

The peptide rapidly normalizes intraocular pressure and preserves the integrity of retinal ganglion cells and optic nerves