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Collectively, these findings suggest that the future therapeutic strategy may shift from single pathway blockage to multi-target homeostasis restoration, thereby enhancing clinical efficacy

Traditional treatments like NSAIDs and corticosteroids provide temporary relief but come with significant drawbacks

Rising at a CAGR of 6.5% , the market is expected to expand by nearly 1.8 times, supported by strong consumer focus on cellular antioxidation, detoxification, endurance performance, and healthy aging philosophies

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4.89 10 6 cm/s in the control group), but it had no influence on the penetration of the targeted 3-PLG-ibu-A-GSH (10.99 10 6 cm/s vs