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Figure 5 consolidates country submissions, formal pricing rules, and expected entrants to gain a qualitative assessment of expected pricing pressure

This year, Eli Lilly published a study in the New England Journal of Medicine on its drug tirzepatide , finding that it caused a 50% decrease in breathing interruption in overweight patients with sleep apnea

As such, abbreviations for the classes start with their first letter (i.e., GSTMA for alpha)

The pattern is notable: nausea did not meaningfully escalate with dose, but constipation did