Hydroxocobalamin, the form most commonly used in the UK, may cause: Injection site reactions (pain, redness, or swelling) Temporary reddish discolouration of urine Rarely, hypersensitivity reactions Very rarely, hypokalaemia in severely deficient patients when treatment is initiated (potassium levels should be monitored in severe deficiency) B12 injections are considered very safe, with no upper tolerable limit established, as excess B12 is excreted in urine
TakanoM.YumotoR.MurakamiT.2006Expression and function of efflux drug transporters in the intestine.1091-2,137161
It was developed for research by Professor Predrag Sikiric at the University of Zagreb
Protective role of melatonin and a combination of vitamin C and vitamin E on lung toxicity induced by chlorpyrifos-ethyl in rats
Systematic review on the use of activated charcoal for gastrointestinal decontamination following acute oral overdose