NICE Clinical Knowledge Summary (CKS) on Amenorrhoea recommends that investigation should include pregnancy testing (essential first step), assessment of thyroid function, prolactin levels, and potentially FSH and LH measurements
It has minimal effect on sleep architecture once sleep begins
Semaglutide is a GLP-1 receptor agonist that interacts with hormone pathways involved in appetite, digestion, and glucose regulation
Potential Side Effects Although both peptides are well-tolerated, some patients may experience: Mild water retention Joint stiffness (temporary) Insulin sensitivity changes (rare) Injection site irritation Patients should always be monitored by a physician trained in peptide therapy, and adjustments can be made to dose or frequency to mitigate any issues
Ipamorelin does its part by stimulating the pituitary gland to release growth hormone in a controlled, pulsatile manner