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Crohns and Colitis 360 2023;5:18
Approval (2017) FDA News Release (March 8th, 2024): FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight FDA News Release (August 15th, 2025): FDA Approves Treatment for Serious Liver Disease Known as MASH OZEMPIC (semaglutide) injection, for subcutaneous use
Eli Lilly and Company originally applied TZT to control blood glucose in 2016
The dosage of semaglutide will likely change over time
11 Mechanisms of Action and Need for Further Study The clinical benefits for both classes of drugs cannot be explained only by effects on glucose-lowering or other established risk factors, leading many to consider novel mechanisms of action
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