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This is called Dupuytrens contracture and Xiaflex has been used to treat this condition
Ta N, Qu C, Wu H, Zhang D, Sun T, Li Y, et al
Sterol responsive element binding protein (SREBP1), a member of the SREBP family, regulates de novo lipogenesis by controlling the transcription of associated genes, such as SCD1 [104, 105]
The administered concentration of PCPA was set at 300 mg/kg via i.p
References Abel ED, Gloyn AL, Evans-Molina C, et al
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