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: 7 2019
To overcome these limitations, a number of pharmacological approaches have been developed over the past decades, but these drugs are generally of fairly limited efficacy, expensive and can in some cases cause significant side effects
PMID 41025003
The practical significance: aging brains accumulate proNGF while losing TrkA receptors, creating a biochemical environment that favors neuronal death over survival
Spiering, D.L
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