Free radicals, such as ROS and RNS, can induce various forms of DNA damage
Pan XH, Tan B, Chin YH, Lee ECZ, Kong G, Chong B, Kueh M, Khoo CM, Mehta A, Majety P, Grandhi GR, Dimitriadis GK, Foo R, Chew NWS, Le Roux CW, Mamas MA, Chan MY
Finally, the relatively small effect size might not be of clinical significance
Yes semaglutide and related drugs shift microbial composition, but these changes do not automatically restore microbial resilience or diversity
These are signals, not conclusions but theyre coming directly from patients, unprompted, and thats worth paying attention to, says the first author, Neil Sehgal, a doctoral student at the University of Pennsylvania in Philadelphia