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The FDA guidance clarifies that this exemption exists to ensure patients don't go without necessary medication during a supply disruption
He S, Hasler BP, Chakravorty S
GLP-1 receptors speed up colon activity While your stomach operates in slow motion, research shows that GLP-1 activation can actually accelerate contractions in the colon
How Trulicity works Trulicity mimics one hormone called GLP-1 (glucagon-like peptide-1), which: Slows food movement through your stomach, helping you feel fuller for longer Communicates with your brains appetite centre to reduce hunger Improves blood sugar control by enhancing insulin function How Mounjaro works Mounjaro activates two hormone receptors: Like Trulicity, it activates the GLP-1 receptor It also activates GIP (glucose-dependent insulinotropic polypeptide), a second gut hormone involved in appetite and blood sugar regulation This dual-action is the primary reason Mounjaro produces greater weight loss and blood sugar improvements than GLP-1-only medications like Trulicity
Ultimately, Zepbound trains your metabolic system, allowing for sustainable weight loss that addresses the underlying biological factors of obesity
