PUFAs are components of the cell membrane lipid bilayer and are important targets of lipid peroxidation during ferroptosis
BPC 157 was studied almost exclusively by the same Croatian team that created it, doing rat study after rat study, while MK-677 was the domain of the Merck Research Laboratories in New Jersey, whose scientists conducted multiple small trials in humans in the 1990s, trying to see if the drug had interesting effects on a variety of surrogate markers
Over a BPC-157 protocol, you want to see it come back down, indicating the destructive phase is resolving and constructive healing is dominant
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doi: 10.3390/IJMS19103041 99 KongB.LiuR.ChengY.CaiX.LiuJ.ZhangD.et al