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Our group recently identified oxamic hydrazide as a potent CSE inhibitor by screening a large chemical library of 161,600 compounds ( 50 value of 13 M with high selectivity over other PLP-dependent enzymes including CBS, alanine aminotransferase and methionine -lyase

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Dietary fiber promotes digestive health through multiple mechanisms: it adds bulk to stool, facilitates intestinal transit, supports beneficial gut microbiota, and helps regulate blood glucose levelscomplementing tirzepatide's glycemic effects

Gracia Graells M, Alcolea Lpez JM