BioNanoScience 13, 426435
For sexual function specifically, the testosterone reduction in PCOS women is actually a net positive because it brings abnormally high levels back toward normal range
According to a clinical primer published in the American Heart Association journal Circulation, semaglutide has been associated with lean mass making up a large share of total weight lost, by some trial estimates approaching 40 percent, and tirzepatide has shown a similar pattern at roughly a third of weight lost
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To explore the functional relevance of these DEGs, gene ontology (GO) enrichment analysis was conducted, revealing that the altered genes were primarily involved in immune response regulation, cytokine production, oxidative stress response, and mitochondrial functions