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Research examining pancreatic tissue fragments from normal and diabetic rats found that ipamorelin evoked significant increases in insulin secretion at concentrations ranging from 10^-12 to 10^-6 M

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Sleep Deprivation Blunts GLP-1 Research published in Annals of Internal Medicine found that even two weeks of mild sleep restriction (6 hours per night) reduced GLP-1 response by up to 20% and increased hunger hormones (ghrelin) significantly

PMID: 27847966 | doi:10.1007/s00109-016-1488-y Chang CH et al

"I trained at the highest level, ate a clean diet, pushed myself, and still, after having kids, my body just wouldnt respond