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Groups switched from WD to LD had a greater average relative abundance of Verrucomicrobia (represented solely by the genus Akkermansia )

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In the pursuit of IOP-targeted gene therapy, various approaches have been investigated, such as targeting the aquaporin 1 gene (281), the prostaglandin F2 receptor (282), RhoA kinase (283), exoenzyme C3 transferase (284, 285), metalloproteinase 1 (286), and myocilin (287)